Vicissitude (?), n. [L. vicissitudo, fr. vicis change, turn: cf. F. vicissitude. See Vicarious.]
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1. Regular change or succession from one thing to another; alternation; mutual succession; interchange.
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God made two great lights . . .
To illuminate the earth and rule the day
In their vicissitude, and rule the night. Milton.
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2. Irregular change; revolution; mutation.
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3. (pl.) Changing conditions of fortune in one's life; life's ups and downs.
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This man had, after many vicissitudes of fortune, sunk at last into abject and hopeless poverty. Macaulay.
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